View Single Post
Old 09-02-2010, 07:32 PM
Sa'ar Chasm's Avatar
Sa'ar Chasm Sa'ar Chasm is offline
Our last, best hope for peace
Join Date: Mar 2003
Location: Sitting (in Ottawa)
Posts: 3,425

Apparently you can buy deuterated, HPLC grade acetonitrile by the litre.
The price is "please inquire".

To put this in perspective, HPLC-grade solvents are generally more expensive than regular solvents because extra effort has gone into removing the impurities. You can generally buy this in 4L bottles.

Acetonitrile saw a spike in price because the industrial process that produced it as a byproduct went belly-up during the economic meltdown. The Great Acetonitrile Shortage is over, but I think the price is still hovering above where it used to be.

Deuterated solvents have had all their Hs replaced by deuterium (the stuff that makes the Enterprise go), a rarer isotope of hydrogen and the stuff that makes heavy water heavy. These are typically sold on a much smaller and can go for $30-$50 for 10 grams (about 10-10 mL).

Putting all that together and then selling it by the litre must be monstrously expensive, as is the HPLC-NMR instrument that requires it. If you want to use it for an experiment, it has to be really important.
The first run through of any experimental procedure is to identify any potential errors by making them.
Reply With Quote